PH regulation of gene expression in fungi

被引:131
作者
Denison, SH [1 ]
机构
[1] Eckerd Coll, Collegium Nat Sci, St Petersburg, FL 33711 USA
关键词
D O I
10.1006/fgbi.2000.1188
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
A system for the regulation of gene expression by ambient (extracellular) pH was first identified in Aspergillus nidulans. This system consists of the products of the pacC and palA, B, C, F, Fl, and I genes. pacC encodes a zinc finger transcription factor and these pal genes encode components of an ambient pH signal transduction pathway. pH regulatory systems have also been identified in other fungi. Components of these regulatory systems are homologous to those in A. nidulans. This review describes the pH regulatory system in A. nidulans and the history of this research and how it relates to other systems, pH regulation in bacteria and animal cells is also briefly discussed. (C) 2000 academic Press.
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页码:61 / 71
页数:11
相关论文
共 52 条
[1]   2 NEW GENES INVOLVED IN SIGNALING AMBIENT PH IN ASPERGILLUS-NIDULANS [J].
ARST, HN ;
BIGNELL, E ;
TILBURN, J .
MOLECULAR & GENERAL GENETICS, 1994, 245 (06) :787-790
[2]  
BANKENHORN D, 1999, J BACTERIOL, V181, P2209
[3]   The tra-3 sex determination gene of Caenorhabditis elegans encodes a member of the calpain regulatory protease family [J].
Barnes, TM ;
Hodgkin, J .
EMBO JOURNAL, 1996, 15 (17) :4477-4484
[4]   Low environmental pH is responsible for the induction of nitric-oxide synthase in macrophages -: Evidence for involvement of nuclear factor-κB activation [J].
Bellocq, A ;
Suberville, S ;
Philippe, C ;
Bertrand, F ;
Perez, J ;
Fouqueray, B ;
Cherqui, G ;
Baud, L .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (09) :5086-5092
[5]  
Bergh KT, 1998, APPL ENVIRON MICROB, V64, P843
[6]   STRUCTURAL GENES FOR PHOSPHATASES IN ASPERGILLUS-NIDULANS [J].
CADDICK, MX ;
ARST, HN .
GENETICAL RESEARCH, 1986, 47 (02) :83-91
[7]   REGULATION OF GENE-EXPRESSION BY PH OF THE GROWTH-MEDIUM IN ASPERGILLUS-NIDULANS [J].
CADDICK, MX ;
BROWNLEE, AG ;
ARST, HN .
MOLECULAR & GENERAL GENETICS, 1986, 203 (02) :346-353
[8]   Identification and cloning of Xp95, a putative signal transduction protein in Xenopus oocytes [J].
Che, SL ;
El-Hodiri, HM ;
Wu, CF ;
Nelman-Gonzalez, M ;
Weil, MM ;
Etkin, LD ;
Clark, RB ;
Kuang, J .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (09) :5522-5531
[9]   SIGNALING OF AMBIENT PH IN ASPERGILLUS INVOLVES A CYSTEINE PROTEASE [J].
DENISON, SH ;
OREJAS, M ;
ARST, HN .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (48) :28519-28522
[10]   Putative membrane components of signal transduction pathways for ambient pH regulation in Aspergillus and meiosis in Saccharomyces are homologous [J].
Denison, SH ;
Negrete-Urtasun, S ;
Mingot, JR ;
Tilburn, J ;
Mayer, WA ;
Goel, A ;
Espeso, EA ;
Peñalva, MA ;
Arst, N .
MOLECULAR MICROBIOLOGY, 1998, 30 (02) :259-264