学术探索
学术期刊
新闻热点
数据分析
智能评审

Cancer vaccines

被引：439
作者：
Pardoll, DM [1 ]
机构：
[1] Johns Hopkins Oncol Ctr, Baltimore, MD 21205 USA
来源：
NATURE MEDICINE | 1998年 / 4卷 / 05期
关键词：
D O I：
10.1038/nm0598supp-525
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Drew Pardoll (Johns Hopkins Oncology Center) examines prospects for therapeutic cancer vaccines. Considering how it is that the immune system fails to recognize and destroy cancer cells, Pardoll discusses contemporary vaccine approaches aimed at exposing cancer antigens to the cellular arm of the immune system, and the first, promising steps toward therapeutic cancer vaccines.
引用
收藏
页码：525 / 531
页数：7
相关论文
共 128 条
  • [1] A dendritic-cell-derived C-C chemokine that preferentially attracts naive T cells
    Adema, GJ
    Hartgers, F
    Verstraten, R
    deVries, E
    Marland, G
    Menon, S
    Foster, J
    Xu, YM
    Nooyen, P
    McClanahan, T
    Bacon, KB
    Figdor, CG
    [J]. NATURE, 1997, 387 (6634) : 713 - 717
  • [2] T-CELL PRIMING VERSUS T-CELL TOLERANCE INDUCED BY SYNTHETIC PEPTIDES
    AICHELE, P
    BRDUSCHARIEM, K
    ZINKERNAGEL, RM
    HENGARTNER, H
    PIRCHER, H
    [J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1995, 182 (01) : 261 - 266
  • [3] Dendritic cells acquire antigen from apoptotic cells and induce class I restricted CTLs
    Albert, ML
    Sauter, B
    Bhardwaj, N
    [J]. NATURE, 1998, 392 (6671) : 86 - 89
  • [4] HUMORAL AND CELL-MEDIATED IMMUNE-RESPONSES TO LIVE RECOMBINANT BCG-HIV VACCINES
    ALDOVINI, A
    YOUNG, RA
    [J]. NATURE, 1991, 351 (6326) : 479 - 482
  • [5] Dendritic cells and the control of immunity
    Banchereau, J
    Steinman, RM
    [J]. NATURE, 1998, 392 (6673) : 245 - 252
  • [6] BEASLEY RP, 1981, LANCET, V2, P1129
  • [7] A NOVEL TYPE OF HUMAN PAPILLOMAVIRUS ASSOCIATED WITH GENITAL NEOPLASIAS
    BEAUDENON, S
    KREMSDORF, D
    CROISSANT, O
    JABLONSKA, S
    WAINHOBSON, S
    ORTH, G
    [J]. NATURE, 1986, 321 (6067) : 246 - 249
  • [8] TREATMENT OF METASTATIC MELANOMA WITH AN AUTOLOGOUS TUMOR-CELL VACCINE - CLINICAL AND IMMUNOLOGICAL RESULTS IN 64 PATIENTS
    BERD, D
    MAGUIRE, HC
    MCCUE, P
    MASTRANGELO, MJ
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 1990, 8 (11) : 1858 - 1867
  • [9] EFFECTIVE TUMOR-IMMUNOTHERAPY DIRECTED AGAINST AN ONCOGENE-ENCODED PRODUCT USING A VACCINIA VIRUS VECTOR
    BERNARDS, R
    DESTREE, A
    MCKENZIE, S
    GORDON, E
    WEINBERG, RA
    PANICALI, D
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (19) : 6854 - 6858
  • [10] MOLECULAR THEMES IN ONCOGENESIS
    BISHOP, JM
    [J]. CELL, 1991, 64 (02) : 235 - 248
12345678910