Controlling calcium entry

被引:76
作者
Taylor, CW [1 ]
机构
[1] Univ Cambridge, Dept Pharmacol, Cambridge CB2 1PD, England
关键词
D O I
10.1016/S0092-8674(02)01197-2
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Ca2+ enters cells through an assortment of Ca2+-permeable channels that respond to different stimuli and couple to different cellular responses. Several different Ca2+ entry pathways can be activated by receptors that stimulate phospholipase C (PLC). Both limbs of this signaling pathway (IP3 and diacylglycerol), PLC itself, and its substrate (PIP2) contribute to the coordinate regulation of these Ca2+ entry pathways.
引用
收藏
页码:767 / 769
页数:3
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