Novel tetracycline resistance determinant from the oral metagenome

被引：77

作者：

Diaz-Torres, ML

McNab, R

Spratt, DA

Villedieu, A

Hunt, N

Wilson, M

Mullany, P

机构：

[1] UCL, Dept Microbiol, Eastman Dent Inst, London WC1X 8LD, England

[2] UCL, Dept Orthodont, Eastman Dent Inst, London WC1X 8LD, England

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2003年 / 47卷 / 04期

关键词：

D O I：

10.1128/AAC.47.4.1430-1432.2003

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A major drawback of most studies on how bacteria become resistant to antibiotics is that they concentrate mainly on bacteria that can be cultivated in the laboratory. In the present study, we cloned part of the oral metagenome and isolated a novel tetracycline resistance gene, tet(37), which inactivates tetracycline.

引用

页码：1430 / 1432

页数：3

共 5 条

[1] Molecular ecology of tetracycline resistance: Development and validation of primers for detection of tetracycline resistance genes encoding ribosomal protection proteins [J].