Rapid and amenable Suzuki coupling reaction in water using microwave and conventional heating

被引：219

作者：

Leadbeater, NE ^{[1
]}

Marco, M ^{[1
]}

机构：

[1] Kings Coll London, Dept Chem, London WC2R 2LS, England

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2003年 / 68卷 / 03期

关键词：

D O I：

10.1021/jo0264022

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

It is possible to prepare biaryls in good yield very rapidy (5-10 min) on small (1 mmol) and larger (10-20 mmol) scales from aryl halides and phenylboronic acid using water as a solvent and palladium acetate as catalyst. The reaction can be performed equally well using microwave and conventional heating, showing that using these conditions probably no nonthermal microwave effects are associated with the impressive speed of the reaction.

引用

页码：888 / 892

页数：5

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