Synthesis and evaluation of N,S-compounds as chiral ligands for transfer hydrogenation of acetophenone

被引:50
作者
Ekegren, JK [1 ]
Roth, P [1 ]
Källström, K [1 ]
Tarnai, T [1 ]
Andersson, PG [1 ]
机构
[1] Uppsala Univ, Dept Organ Chem, SE-75121 Uppsala, Sweden
关键词
D O I
10.1039/b208907f
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
New nitrogen- and sulfur-containing compounds, bicyclic and monocyclic, were prepared and evaluated as ligands in the transfer hydrogenation of acetophenone. Utilising [Ir(COD)Cl](2) as metal precursor the best result, 80% ee, was obtained using a bicyclic sulfoxide ligand.
引用
收藏
页码:358 / 366
页数:9
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