Mechanisms of metastasis

被引：66

作者：

Ahmad, A ^{[1
]}

Hart, IR ^{[1
]}

机构：

[1] UMDS, St Thomas Hosp, Rayne Inst, ICRF Lab,Richard Dimbleby Dept Canc Res, London SE1 7EH, England

来源：

CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY | 1997年 / 26卷 / 03期

关键词：

D O I：

10.1016/S1040-8428(97)10002-6

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Whilst our understanding of the biology of the metastatic cascade has improved significantly in recent years, sadly this has not been matched by dramatic improvements in eradication of solid tumour metastases in patients. As the regulatory mechanisms underlying tumour angiogenesis and ECM degradation become apparent, novel anti-metastatic strategies are being developed and early studies suggest they hold some promise.

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页码：163 / 173

页数：11

相关论文

共 126 条

[1]

ALBELDA SM, 1993, LAB INVEST, V68, P4

[2] INTEGRINS AND OTHER CELL-ADHESION MOLECULES [J].

ALBELDA, SM ;

BUCK, CA .

FASEB JOURNAL, 1990, 4 (11) :2868-2880

[3]

ALBELDA SM, 1990, CANCER RES, V50, P6757

[4] TUMOR-CELL INVASION INHIBITED BY TIMP-2 [J].

ALBINI, A ;

MELCHIORI, A ;

SANTI, L ;

LIOTTA, LA ;

BROWN, PD ;

STETLERSTEVENSON, WG .

JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1991, 83 (11) :775-779

[5]

ALTOMONTE M, 1993, CANCER RES, V53, P3343

[6]

ARESU O, 1991, INVAS METAST, V11, P2

[7] RAS ONCOGENE MEDIATED INDUCTION OF A 92KDA METALLOPROTEINASE - STRONG CORRELATION WITH THE MALIGNANT PHENOTYPE [J].

BALLIN, M ;

GOMEZ, DE ;

SINHA, CC ;

THORGEIRSSON, UP .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1988, 154 (03) :832-838

[8] A NOVEL METALLOPROTEINASE GENE SPECIFICALLY EXPRESSED IN STROMAL CELLS OF BREAST CARCINOMAS [J].

BASSET, P ;

BELLOCQ, JP ;

WOLF, C ;

STOLL, I ;

HUTIN, P ;

LIMACHER, JM ;

PODHAJCER, OL ;

CHENARD, MP ;

RIO, MC ;

CHAMBON, P .

NATURE, 1990, 348 (6303) :699-704

[9] DISSECTING TUMOR-CELL INVASION - EPITHELIAL-CELLS ACQUIRE INVASIVE PROPERTIES AFTER THE LOSS OF UVOMORULIN-MEDIATED CELL CELL-ADHESION [J].

BEHRENS, J ;

MAREEL, MM ;

VANROY, FM ;

BIRCHMEIER, W .

JOURNAL OF CELL BIOLOGY, 1989, 108 (06) :2435-2447

[10] THE ROLE OF CELL-ADHESION MOLECULES IN CANCER INVASION AND METASTASIS [J].

BEHRENS, J .

BREAST CANCER RESEARCH AND TREATMENT, 1993, 24 (03) :175-184

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