Tailoring the mechanical properties of polyacrylamide-based hydrogels

被引：31

作者：

Baker, Bryan A. ^{[1
]}

Murff, Rebecca L. ^{[2
]}

Milam, Valeria T. ^{[1
,2
,3
]}

机构：

[1] Georgia Inst Technol, Sch Mat Sci & Engn, Atlanta, GA 30332 USA

[2] Georgia Inst Technol, Wallace H Coulter Dept Biomed Engn, Atlanta, GA 30332 USA

[3] Georgia Inst Technol, Petit Inst Bioengn & Biosci, Atlanta, GA 30332 USA

来源：

POLYMER | 2010年 / 51卷 / 10期

基金：

美国国家科学基金会;

关键词：

Hydrogel; Rheology; Polyacrylamide; RHEOLOGICAL PROPERTIES; CELL; DENSITY; COPOLYMER; BEHAVIOR; GELS;

D O I：

10.1016/j.polymer.2010.02.022

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Here, we studied the mechanical properties of polyacrylic acid-co-polyacrylamide (pAAc/pAAm) and polyacrylate-co-polyacrylamide (pNaAc/pAAm)-based hydrogels as a function of composition and total polymer content. While both polyacrylate and polyacrylic acid are weakly-charged polyelectrolytes with carboxylate side groups, they exhibit different behavior as copolymers with polyacrylamide. In swelling studies the highest degree of volumetric expansion occurs in the polyacrylate-rich hydrogels. Rheological measurements indicate that the shear storage modulus of the hydrogels typically increases with the percentage of polyacrylamide for a given polymer volume fraction; however, the simultaneous strengthening and embrittling effects of polyacrylamide as a copolymer are more dramatic for the pNaAc/pAAm hydrogels. (C) 2010 Elsevier Ltd. All rights reserved.

引用

页码：2207 / 2214

页数：8

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