Growth hormone treatment strategy for short children born small for gestational age

被引：5

作者：

Czernichow, P ^{[1
]}

机构：

[1] Hop Robert Debre, Dept Paediat Endocrinol, FR-75019 Paris, France

来源：

HORMONE RESEARCH | 2004年 / 62卷

关键词：

growth hormone; small for gestational age; short stature; treatment; insulin like growth factor-I;

D O I：

10.1159/000080515

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Several studies performed in the last 15 years have shown that growth hormone (GH) induces a profound catch-up in height in short children born small for gestational age (SGA). We know from more recent studies that final height can be normalized through GH treatment. In Europe, GH is now a recognized indication, enabling treatment of short children born SGA. Treatment is given to the most severe growth-retarded children after the age of 4 years. A dose of 0.035 mg/kg per day is recommended. However, in our opinion a higher dose would be more efficient in very short children, especially if they are treated later in childhood. Copyright (C) 2004 S. Karger AG, Basel.

引用

页码：137 / 140

页数：4

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