A photolabile 'traceless' linker for solid-phase organic synthesis

被引：22

作者：

Horton, JR ^{[1
]}

Stamp, LM ^{[1
]}

Routledge, A ^{[1
]}

机构：

[1] Univ Leeds, Sch Chem, Leeds LS2 9JT, W Yorkshire, England

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 47期

关键词：

D O I：

10.1016/S0040-4039(00)01644-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A photolabile linker based on a thiohydroxamic acid has been shown to be an efficient 'traceless' linker, revealing an aliphatic CH bond on photolysis at 350 nm. Methods for the synthesis, loading and photolytic cleavage of the linker are described. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：9181 / 9184

页数：4

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