Colocalization of GABA and glycine in the rat dorsal column nuclei

被引：54

作者：

Popratiloff, A ^{[1
]}

Valtschanoff, JG ^{[1
]}

Rustioni, A ^{[1
]}

Weinberg, RJ ^{[1
]}

机构：

[1] UNIV N CAROLINA,DEPT CELL BIOL & ANAT,CHAPEL HILL,NC 27599

来源：

BRAIN RESEARCH | 1996年 / 706卷 / 02期

关键词：

postsynaptic inhibition; presynaptic inhibition; interneuron; somatosensory; cuneate nucleus; gracile nucleus;

D O I：

10.1016/0006-8993(95)01280-X

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

About half the neurons in the rat dorsal column nuclei were immunopositive for glycine or for GABA; these were smaller than immunonegative neurons. In double-stained material, 29% of stained neurons were immunopositive for glycine only, 29% immunopositive for GABA only, and 42% for both antigens. The results resemble those reported for spinal cord laminae that receive fast-conducting primary afferents, and suggest that glycine is an inhibitory neurotransmitter in the dorsal column nuclei.

引用

页码：308 / 312

页数：5

共 29 条

[1]

ARAKI J, 1988, NEUROSCIENCE, V5, P613

[2] NEUROCHEMICAL TRANSMISSION IN THE DORSAL COLUMN NUCLEI [J].

BANNA, NR ;

JABBUR, SJ .

SOMATOSENSORY AND MOTOR RESEARCH, 1989, 6 (03) :237-251

[3] GABAERGIC NEURONS ARE PRESENT IN THE DORSAL COLUMN NUCLEI BUT NOT IN THE VENTROPOSTERIOR COMPLEX OF RATS [J].

BARBARESI, P ;

SPREAFICO, R ;

FRASSONI, C ;

RUSTIONI, A .

BRAIN RESEARCH, 1986, 382 (02) :305-326

[4] INHIBITORY NEUROTRANSMISSION IN RAT SPINAL-CORD - COLOCALIZATION OF GLYCINE-RECEPTOR AND GABA(A)-RECEPTOR AT GABAERGIC SYNAPTIC CONTACTS DEMONSTRATED BY TRIPLE IMMUNOFLUORESCENCE STAINING [J].

BOHLHALTER, S ;

MOHLER, H ;

FRITSCHY, JM .

BRAIN RESEARCH, 1994, 642 (1-2) :59-69

[5]

BROMAN J, 1994, ANAT EMBRYOL, V189, P181

[6] CALCITONIN GENE-RELATED PEPTIDE-POSITIVE NEURONS AND FIBERS IN THE CAT DORSAL COLUMN NUCLEI [J].

FABRI, M ;

CONTI, F .

NEUROSCIENCE, 1990, 35 (01) :167-174

[7] GLYCINE RECEPTOR DISTRIBUTION IN MOUSE CNS - AUTORADIOGRAPHIC LOCALIZATION OF [H-3]STRYCHNINE BINDING-SITES [J].

FROSTHOLM, A ;

ROTTER, A .

BRAIN RESEARCH BULLETIN, 1985, 15 (05) :473-486

[8] INTRACELLULAR STAINING STUDY OF THE FELINE CUNEATE NUCLEUS .2. THALAMIC PROJECTING NEURONS [J].

FYFFE, REW ;

CHEEMA, SS ;

LIGHT, AR ;

RUSTIONI, A .

JOURNAL OF NEUROPHYSIOLOGY, 1986, 56 (05) :1284-1296

[9] MICRO-IONTOPHORETIC STUDIES ON NEURONES IN CUNEATE NUCLEUS [J].

GALINDO, A ;

KRNJEVIC, K ;

SCHWARTZ, S .

JOURNAL OF PHYSIOLOGY-LONDON, 1967, 192 (02) :359-&

[10]

JONES EG, 1987, CEREB CORTEX, V6, P237

← 1 2 3 →