Endothelium-microenvironment interactions in the developing embryo and in the adult

被引:111
作者
Red-Horse, Kristy [1 ]
Crawford, Yongping [1 ]
Shojaei, Farbod [1 ]
Ferrara, Napoleone [1 ]
机构
[1] Genentech Inc, San Francisco, CA 94080 USA
关键词
D O I
10.1016/j.devcel.2007.01.013
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The vascular endothelium is best known for its role in oxygen and nutrient delivery to the various tissues. Growing evidence supports a far more complex role in tissue homeostasis. In particular, reciprocal interactions between endothelial cells and the local microenvironment may regulate organ development and pattern formation. Such interactions appear to be important also in the adult, in normal and pathological conditions.
引用
收藏
页码:181 / 194
页数:14
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