Neuronal survival: Early dependence on Schwann cells

被引：38

作者：

Davies, AM ^{[1
]}

机构：

[1] Univ St Andrews, Sch Biol & Med Sci, St Andrews KY16 9TS, Fife, Scotland

来源：

CURRENT BIOLOGY | 1998年 / 8卷 / 01期

关键词：

D O I：

10.1016/S0960-9822(98)70009-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Schwann cells fail to develop in mouse embryos lacking functional ErbB3 neuregulin receptors, and most sensory and motor neurons subsequently die in these mice. As ErbB3 acts cell autonomously in Schwann cell development but not in neuronal survival, neurons may depend on Schwann cells for survival.

引用

页码：R15 / R18

页数：4

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