Mitogenesis by ligands of nuclear receptors: an attractive model for the study of the molecular mechanisms implicated in liver growth

被引:39
作者
Columbano, A [1 ]
Ledda-Columbano, GM [1 ]
机构
[1] Univ Cagliari, Unit Oncol & Mol Pathol, Dept Toxicol, I-09124 Cagliari, Italy
关键词
D O I
10.1038/sj.cdd.4401113
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
[No abstract available]
引用
收藏
页码:S19 / S21
页数:3
相关论文
共 19 条
[1]  
AKERMAN P, 1992, AM J PHYSIOL, V263, P579
[2]   TOO MANY RODENT CARCINOGENS - MITOGENESIS INCREASES MUTAGENESIS [J].
AMES, BN ;
GOLD, LS .
SCIENCE, 1990, 249 (4972) :970-971
[3]   THYROID-HORMONE (T-3) INHIBITS CIPROFIBRATE-INDUCED TRANSCRIPTION OF GENES ENCODING BETA-OXIDATION ENZYMES - CROSS-TALK BETWEEN PEROXISOME PROLIFERATOR AND T-3 SIGNALING PATHWAYS [J].
CHU, RY ;
MADISON, LD ;
LIN, YL ;
KOPP, P ;
RAO, MS ;
JAMESON, JL ;
REDDY, JK .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1995, 92 (25) :11593-11597
[4]   Peroxisome proliferator-activated receptor-α-/- mice show enhanced hepatocyte proliferation in response to the hepatomitogen 1,4-bis[2-(3,5-dichloropyridyloxy)] benzene, a ligand of constitutive androstane receptor [J].
Columbano, A ;
Ledda-Columbano, GM ;
Pibiri, M ;
Concas, D ;
Reddy, JK ;
Rao, MS .
HEPATOLOGY, 2001, 34 (02) :262-266
[5]   Liver regeneration .8. Liver regeneration versus direct hyperplasia [J].
Columbano, A ;
Shinozuka, H .
FASEB JOURNAL, 1996, 10 (10) :1118-1128
[6]   Liver failure and defective hepatocyte regeneration in interleukin-6-deficient mice [J].
Cressman, DE ;
Greenbaum, LE ;
DeAngelis, RA ;
Ciliberto, G ;
Furth, EE ;
Poli, V ;
Taub, R .
SCIENCE, 1996, 274 (5291) :1379-1383
[7]   The hallmarks of cancer [J].
Hanahan, D ;
Weinberg, RA .
CELL, 2000, 100 (01) :57-70
[8]  
Higgins GM, 1931, ARCH PATHOL, V12, P186
[9]   Selective ablation of retinoid X receptor α in hepatocytes impairs their lifespan and regenerative capacity [J].
Imai, T ;
Jiang, M ;
Kastner, P ;
Chambon, P ;
Metzger, D .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (08) :4581-4586
[10]   Liver regeneration: Prospects for therapy based on new technologies [J].
Kay, MA ;
Fausto, N .
MOLECULAR MEDICINE TODAY, 1997, 3 (03) :108-115