The effect of rTMS over the cerebellum in normal human volunteers on peg-board movement performance

被引：51

作者：

Miall, RC ^{[1
]}

Christensen, LOD

机构：

[1] Univ Birmingham, Sch Psychol, Behav Brain Sci Ctr, Birmingham B15 2TT, W Midlands, England

[2] Univ Oxford, Physiol Lab, Oxford OX1 3PT, England

来源：

NEUROSCIENCE LETTERS | 2004年 / 371卷 / 2-3期

基金：

英国惠康基金;

关键词：

cerebellum; transcranial magnetic stimulation; sensorimotor control;

D O I：

10.1016/j.neulet.2004.08.067

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Low frequency rTMS over the paramedian part of the right cerebellum was used to test the effects of TMS-induced disruption of the cerebellum on performance of the 10-hole pegboard task. A test group (n = 14) showed significantly increased movement times lasting about 3 min after the 5-min 1 Hz rTMS train, compared to a control group who received no rTMS (n = 14), tested in a parallel group design. The increase was greatest for the hand ipsilateral to the stimulation, but the difference between the two hands was not statistically significant. These results suggest that the rTMS affects cerebellar excitability and cause a short-lasting bilateral change in sensory-motor performance. (C) 2004 Elsevier Ireland Ltd. All rights reserved.

引用

页码：185 / 189

页数：5

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