Platelet Aggregation and Endothelial Function in Patients with Complicated Essential Hypertension (Ischemic Stroke) and Coronary Heart Disease

被引：7

作者：

Shimohina, N. Yu. ^{[1
]}

Petrova, M. M. ^{[1
]}

Savchenko, A. A. ^{[1
]}

Smertina, E. G. ^{[2
]}

Ionova, V. G. ^{[1
]}

Tanashyan, M. M. ^{[1
]}

机构：

[1] VF Voino Yasenetskii Krasnoyarsk State Med Univ, Krasnoyarsk, Russia

[2] NS Karpovich Municipal Hosp 6, Krasnoyarsk, Russia

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2010年 / 149卷 / 01期

关键词：

platelet aggregation; endothelial dysfunction; VON-WILLEBRAND-FACTOR; CARDIOVASCULAR-DISEASE; BLOOD;

D O I：

10.1007/s10517-010-0864-9

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

In patients with complicated essential hypertension (ischemic stroke) and coronary heart disease, inductors of platelet aggregation in various doses induced "paradoxical" changes in platelet aggregation activity reflecting the degree of decompensation under conditions of persistent endothelial dysfunction. Aggregation inductors in low doses were shown to have a greater diagnostic significance. The content of endothelial dysfunction markers in the blood was persistently elevated under these conditions.

引用

页码：18 / 20

页数：3

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