A family history and direct interview study of the familial aggregation of substance abuse: the adolescent substance abuse study

被引:53
作者
Miles, DR
Stallings, MC
Young, SE
Hewitt, JK
Crowley, TJ
Fulker, DW
机构
[1] Univ Colorado, Inst Behav Genet, Boulder, CO 80309 USA
[2] Univ Colorado, Hlth Sci Ctr, Dept Psychiat, Boulder, CO 80309 USA
关键词
drug and alcohol abuse; family study; family history;
D O I
10.1016/S0376-8716(97)00156-7
中图分类号
R194 [卫生标准、卫生检查、医药管理];
学科分类号
摘要
The adolescent substance abuse (ASA) study collected information concerning drug use and psychopathology on male adolescent probands in treatment for substance abuse and also on matched control adolescents, as well as all available family members of both groups. Information was obtained through direct interview and the family history method of assessment. Both methods revealed greater alcohol and drug use, conduct disorder (CD) and antisocial personality disorder (ASP) in the relatives of treatment probands as compared with control relatives. These results suggest familial transmission, not only for alcohol abuse, but also for non-alcohol substance abuse. Familial transmission for CD and ASP is also evident for both male and female relatives, although the prevalence of these disorders is significantly greater in males than females. (C) 1998 Elsevier Science Ireland Ltd.
引用
收藏
页码:105 / 114
页数:10
相关论文
共 40 条
[1]  
ALLEN MH, 1986, PSYCHOPATHOLOGY ADDI, P17
[2]  
ANDREASEN NC, 1986, ARCH GEN PSYCHIAT, V43, P421
[3]  
Blom G., 1958, STAT ESTIMATES TRANS
[4]   The efficacy of 2 different dosages of methylphenidate in treating adults with attention-deficit hyperactivity disorder [J].
Bouffard, R ;
Hechtman, L ;
Minde, K ;
Iaboni-Kassab, F .
CANADIAN JOURNAL OF PSYCHIATRY-REVUE CANADIENNE DE PSYCHIATRIE, 2003, 48 (08) :546-554
[5]   An adoption study of drug abuse dependency in females [J].
Cadoret, RJ ;
Yates, WR ;
Troughton, E ;
Woodworth, G ;
Stewart, MA .
COMPREHENSIVE PSYCHIATRY, 1996, 37 (02) :88-94
[6]  
CADORET RJ, 1995, ARCH GEN PSYCHIAT, V52, P42
[7]  
CADORET RJ, 1986, ARCH GEN PSYCHIAT, V43, P1131
[8]  
CADORET RJ, 1995, ARCH GEN PSYCHIAT, V52, P916
[9]  
CAREY G, 1994, UNDERSTANDING PREVEN, V2, P21
[10]   FAMILIAL INCIDENCE OF ALCOHOLISM - REVIEW [J].
COTTON, NS .
JOURNAL OF STUDIES ON ALCOHOL, 1979, 40 (01) :89-116