PROPHECY -: a database for high-resolution phenomics

被引:29
作者
Fernandez- Ricaud, L
Warringer, J
Ericson, E
Pylvänäinen, I
Kemp, GJL
Nerman, O
Blomberg, A
机构
[1] Gothenburg Univ, Dept Cell & Mol Biol, Lundgerg Lab, S-41390 Gothenburg, Sweden
[2] Chalmers Univ Technol, Dept Comp Sci, SE-41296 Gothenburg, Sweden
关键词
D O I
10.1093/nar/gki126
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The rapid recent evolution of the field phenomics-the genome-wide study of gene dispensability by quantitative analysis of phenotypes-has resulted in an increasing demand for new data analysis and visualization tools. Following the introduction of a novel approach for precise, genome-wide quantification of gene dispensability in Saccharomyces cerevisiae we here announce a public resource for mining, filtering and visualizing phenotypic data-the PROPHECY database. PROPHECY is designed to allow easy and flexible access to physiologically relevant quantitative data for the growth behaviour of mutant strains in the yeast deletion collection during conditions of environmental challenges. PROPHECY is publicly accessible at http://prophecy.lundberg.gu.se.
引用
收藏
页码:D369 / D373
页数:5
相关论文
共 7 条
  • [1] The GRID: The General Repository for Interaction Datasets
    Breitkreutz, BJ
    Stark, C
    Tyers, M
    [J]. GENOME BIOLOGY, 2003, 4 (03)
  • [2] SGD:: Saccharomyces Genome Database
    Cherry, JM
    Adler, C
    Ball, C
    Chervitz, SA
    Dwight, SS
    Hester, ET
    Jia, YK
    Juvik, G
    Roe, T
    Schroeder, M
    Weng, SA
    Botstein, D
    [J]. NUCLEIC ACIDS RESEARCH, 1998, 26 (01) : 73 - 79
  • [3] Functional profiling of the Saccharomyces cerevisiae genome
    Giaever, G
    Chu, AM
    Ni, L
    Connelly, C
    Riles, L
    Véronneau, S
    Dow, S
    Lucau-Danila, A
    Anderson, K
    André, B
    Arkin, AP
    Astromoff, A
    El Bakkoury, M
    Bangham, R
    Benito, R
    Brachat, S
    Campanaro, S
    Curtiss, M
    Davis, K
    Deutschbauer, A
    Entian, KD
    Flaherty, P
    Foury, F
    Garfinkel, DJ
    Gerstein, M
    Gotte, D
    Güldener, U
    Hegemann, JH
    Hempel, S
    Herman, Z
    Jaramillo, DF
    Kelly, DE
    Kelly, SL
    Kötter, P
    LaBonte, D
    Lamb, DC
    Lan, N
    Liang, H
    Liao, H
    Liu, L
    Luo, CY
    Lussier, M
    Mao, R
    Menard, P
    Ooi, SL
    Revuelta, JL
    Roberts, CJ
    Rose, M
    Ross-Macdonald, P
    Scherens, B
    [J]. NATURE, 2002, 418 (6896) : 387 - 391
  • [4] Systematic functional analysis of the Caenorhabditis elegans genome using RNAi
    Kamath, RS
    Fraser, AG
    Dong, Y
    Poulin, G
    Durbin, R
    Gotta, M
    Kanapin, A
    Le Bot, N
    Moreno, S
    Sohrmann, M
    Welchman, DP
    Zipperlen, P
    Ahringer, J
    [J]. NATURE, 2003, 421 (6920) : 231 - 237
  • [5] MIPS:: a database for genomes and protein sequences
    Mewes, HW
    Frishman, D
    Güldener, U
    Mannhaupt, G
    Mayer, K
    Mokrejs, M
    Morgenstern, B
    Münsterkötter, M
    Rudd, S
    Weil, B
    [J]. NUCLEIC ACIDS RESEARCH, 2002, 30 (01) : 31 - 34
  • [6] High-resolution yeast phenomics resolves different physiological features in the saline response
    Warringer, J
    Ericson, E
    Fernandez, L
    Nerman, O
    Blomberg, A
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (26) : 15724 - 15729
  • [7] Automated screening in environmental arrays allows analysis of quantitative phenotypic profiles in Saccharomyces cerevisiae
    Warringer, J
    Blomberg, A
    [J]. YEAST, 2003, 20 (01) : 53 - 67