Electrochemical Method for the Determination of Enantiomeric Excess of Binol Using Redox-Active Boronic Acids as Chiral Sensors

被引：80

作者：

Mirri, Giorgio ^{[1
]}

Bull, Steven D. ^{[2
]}

Horton, Peter N. ^{[3
]}

James, Tony D. ^{[2
]}

Male, Louise ^{[1
]}

Tucker, James H. R. ^{[1
]}

机构：

[1] Univ Birmingham, Sch Chem, Birmingham B15 2TT, W Midlands, England

[2] Univ Bath, Dept Chem, Bath BA2 7AY, Avon, England

[3] Univ Southampton, EPSRC Natl Crystallog Serv, Southampton SO17 1BJ, Hants, England

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2010年 / 132卷 / 26期

关键词：

RECOGNITION; PROTOCOLS;

D O I：

10.1021/ja103462x

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A chiral ferrocene-based boronic acid interacts with (R)- and (S)-Binol to form two complexes that exhibit significantly different. ferrocene-based electrode potentials. This difference in redox behavior can be exploited to demonstrate in principle how high levels of enantiomeric excess in a mixture of enantiomers can be quantified and read-out using an electrochemical method.

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页码：8903 / +

页数：4

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