A method and server for predicting damaging missense mutations

被引：10332

作者：

Adzhubei, Ivan A. ^{[1
]}

Schmidt, Steffen ^{[2
]}

Peshkin, Leonid ^{[3
]}

Ramensky, Vasily E. ^{[4
]}

Gerasimova, Anna ^{[5
,6
]}

Bork, Peer ^{[7
]}

Kondrashov, Alexey S. ^{[5
,6
]}

Sunyaev, Shamil R. ^{[1
]}

机构：

[1] Harvard Univ, Sch Med, Div Genet, Brigham & Womens Hosp, Boston, MA 02115 USA

[2] Max Planck Inst Dev Biol, Dept Biochem, Tubingen, Germany

[3] Harvard Univ, Sch Med, Dept Syst Biol, Boston, MA USA

[4] Russian Acad Sci, VA Engelhardt Mol Biol Inst, Moscow, Russia

[5] Univ Michigan, Inst Life Sci, Ann Arbor, MI USA

[6] Univ Michigan, Dept Ecol & Evolutionary Biol, Ann Arbor, MI USA

[7] European Mol Biol Lab, Heidelberg, Germany

来源：

NATURE METHODS | 2010年 / 7卷 / 04期

关键词：

PROTEIN FUNCTION;

D O I：

10.1038/nmeth0410-248

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：248 / 249

页数：3

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