Synthesis of novel carbocyclic nucleosides with a cyclopentenyl ring:: Homocarbovir and analogues

被引：13

作者：

Balo, C ^{[1
]}

Blanco, JM ^{[1
]}

Fernández, F ^{[1
]}

Lens, E ^{[1
]}

López, C ^{[1
]}

机构：

[1] Univ Santiago, Fac Farm, Dept Quim Organ, E-15706 Santiago De Compostela, Spain

来源：

TETRAHEDRON | 1998年 / 54卷 / 12期

关键词：

D O I：

10.1016/S0040-4020(98)83020-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Several synthetic strategics have been used to prepare (+)-cis-4-(aminomethyl)-2-cyclopentenylmethanol (6) from norbornadiene. Amino alchohol 6 has been then used to prepare an homologue of carbovir and its congeners. Alternatively, a synthetic intermediate in the preparation of 6 can be used in a convergent mode to prepare the corresponding adenine and inosine analogues. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：2833 / 2842

页数：10

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