Intra-herd prevalence and colonisation dynamics of Methicillin-resistant Staphylococcus aureus (MRSA) in two pig breeding herds

被引:9
作者
Nathaus, Rolf [1 ]
Blaha, Thomas [2 ]
Tegeler, Regina [2 ]
Meemken, Diana [2 ]
机构
[1] Vet Team Reken, D-48734 Reken, Germany
[2] Univ Vet Med Hannover, Aussenstelle Epidemiol, Hannover, Germany
来源
BERLINER UND MUNCHENER TIERARZTLICHE WOCHENSCHRIFT | 2010年 / 123卷 / 5-6期
关键词
livestock-associated MRSA; laMRSA; ST398; pig; ST398; HUMANS; INFECTIONS; ANIMALS; CC398;
D O I
10.2376/0005-9366-123-221
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
This study presents data on the intra-herd prevalence and colonisation dynamics of Methicillin-resistant (MRSA) and Methicillin-sensible (MSSA) Staphylococcus aureus in two independent pig herds located in the Northwest of Germany. Swabs taken from the nasal cavity of sows and piglets, from the udder of the sows and from the direct environment of the pigs were tested microbiologically for MRSA and MSSA. The piglets were identified individually, tested at birth and then swabbed again every 3 weeks from birth to sale at the end of nursery with 25 kg (farm A), and at slaughter respectively (farm B). The intra-herd prevalence differed between the two farms remarkably. In addition, both farms differed concerning the point in time of the first detection of MRSA in piglets: While MRSA was detected in piglets on farm A within three days after farrowing, positive results in piglets did not occur before three weeks of life on farm B. An MRSA-positive result of the sow increased the number of MRSA-positive piglets on days 1-3. Moreover the results of this study support the suggestion, that an early colonisation of the piglets with Methicillin-sensitive S. aureus (MSSA) has a protective effect. Over time, the pigs changed their microbiological status of colonisation. Samples from the surroundings of the pigs revealed that the proper cleaning and disinfection on one of the study farms had a reducing effect on the MRSA occurrence in the farrowing pens and in the flat deck.
引用
收藏
页码:221 / 228
页数:8
相关论文
共 29 条
[1]  
[Anonymous], 2007, EFSA J, V129, P1, DOI DOI 10.2903/J.EFSA.2007.129R
[2]  
[Anonymous], 2009, The EFSA Journal, V993, P1, DOI DOI 10.2903/J.EFSA.2009.993
[3]   Clonal comparison of Staphylococcus aureus isolates from healthy pig farmers, human controls, and pigs [J].
Armand-Lefevre, L ;
Ruimy, R ;
Andremont, A .
EMERGING INFECTIOUS DISEASES, 2005, 11 (05) :711-714
[4]   Antimicrobial resistance in commensal flora of pig farmers [J].
Aubry-Damon, H ;
Grenet, K ;
Sall-Ndiaye, P ;
Che, D ;
Cordeiro, E ;
Bougnoux, ME ;
Rigaud, E ;
Le Strat, Y ;
Lemanissier, V ;
Armand-Lefèvre, L ;
Delzescaux, D ;
Desenclos, JC ;
Liénard, M ;
Andremont, A .
EMERGING INFECTIOUS DISEASES, 2004, 10 (05) :873-879
[5]   NATURALLY OCCURRING METHICILLIN-RESISTANT STAPHYLOCOCCI [J].
BARBER, M .
JOURNAL OF GENERAL MICROBIOLOGY, 1964, 35 (02) :183-+
[6]  
BERNER H, 1981, TIERARZTL UMSCHAU, V36, P250
[7]  
BROENS EM, 2008, P 20 IPVS C DURB S A
[8]  
BROENS EM, 2008, PREVALENCE STUDY RIS
[9]   Nasal Colonization of Humans with Methicillin-Resistant Staphylococcus aureus (MRSA) CC398 with and without Exposure to Pigs [J].
Cuny, Christiane ;
Nathaus, Rolf ;
Layer, Franziska ;
Strommenger, Birgit ;
Altmann, Doris ;
Witte, Wolfgang .
PLOS ONE, 2009, 4 (08)
[10]   Competition between methicillin-sensitive and -resistant Staphylococcus aureus in the anterior nares [J].
Dall'Antonia, M ;
Coen, PG ;
Wilks, M ;
Whiley, A ;
Millar, M .
JOURNAL OF HOSPITAL INFECTION, 2005, 61 (01) :62-67