Unusual and unexpected reactivity of t-butyl dicarbonate (Boc2O)with alcohols in the presence of magnesium perchlorate.: A new and general route to t-butyl ethers

被引：73

作者：

Bartoli, G ^{[1
]}

Bosco, M ^{[1
]}

Locatelli, M ^{[1
]}

Marcantoni, E ^{[1
]}

Melchiorre, P ^{[1
]}

Sambri, L ^{[1
]}

机构：

[1] Dipartimento Chim Organ A Mangini, I-40136 Bologna, Italy

来源：

ORGANIC LETTERS | 2005年 / 7卷 / 03期

关键词：

D O I：

10.1021/ol047704o

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new mild method for protecting alcohols as t-butyl ethers is reported. The reaction proceeds with Mg(ClO4)(2) and Boc(2)O and shows general applicability. The deprotection of t-butyl ethers has also been revisited. Preliminary results indicate the CeCl3.7H(2)O/Nal system is a very suitable catalyst for their removal.

引用

页码：427 / 430

页数：4

共 23 条

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