Post-stroke dysphagia: A review and design considerations for future trials

被引:329
作者
Cohen, David L. [1 ]
Roffe, Christine [2 ]
Beavan, Jessica [3 ]
Blackett, Brenda [4 ]
Fairfield, Carol A. [5 ]
Hamdy, Shaheen [6 ]
Havard, Di [7 ]
McFarlane, Mary [8 ]
McLauglin, Carolee [9 ]
Randall, Mark [10 ]
Robson, Katie [7 ]
Scutt, Polly [7 ]
Smith, Craig [11 ]
Smithard, David [12 ]
Sprigg, Nikola [7 ]
Warusevitane, Anushka [13 ]
Watkins, Caroline [14 ]
Woodhouse, Lisa [7 ]
Bath, Philip M. [7 ]
机构
[1] Northwick Pk Hosp & Clin Res Ctr, Care Older People, London, England
[2] Keele Univ, Univ Hosp North Midlands, Stroke Res, Keele, Staffs, England
[3] Royal Derby Hosp, Stroke, Derby, England
[4] Salford Royal Hosp, Nutr, Salford, Lancs, England
[5] Univ Reading, Sch Psychol & Clin Language Sci, Reading RG6 2AH, Berks, England
[6] Univ Manchester, Inst Inflammat & Repair, Manchester M13 9PL, Lancs, England
[7] Univ Nottingham, Div Clin Neurosci, Stroke Trials Unit, Nottingham NG7 2RD, England
[8] Northwick Pk Hosp & Clin Res Ctr, Speech & Language, Harrow, Middx, England
[9] Royal Victoria Hosp, Speech & Language, Belfast, Antrim, North Ireland
[10] Leeds Teaching Hosp, Neurol, Leeds, W Yorkshire, England
[11] Univ Manchester, Stroke & Vasc Res Ctr, Manchester M13 9PL, Lancs, England
[12] Princess Royal Univ Hosp, Elderly Med, Orpington, Kent, England
[13] Univ Hosp North Midlands, Acute Stroke Unit, Stoke On Trent, Staffs, England
[14] Univ Cent Lancashire, Coll Hlth & Wellbeing, Preston PR1 2HE, Lancs, England
基金
美国国家卫生研究院;
关键词
Stroke; dysphagia; treatment; randomized controlled trial; design; pneumonia; aspiration; rehabilitation; FIBEROPTIC ENDOSCOPIC EVALUATION; ACUTE ISCHEMIC-STROKE; OROPHARYNGEAL DYSPHAGIA; MEDICAL COMPLICATIONS; SWALLOWING FUNCTION; SILENT ASPIRATION; NATURAL-HISTORY; PNEUMONIA; CARE; RISK;
D O I
10.1177/1747493016639057
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Post-stroke dysphagia (a difficulty in swallowing after a stroke) is a common and expensive complication of acute stroke and is associated with increased mortality, morbidity, and institutionalization due in part to aspiration, pneumonia, and malnutrition. Although most patients recover swallowing spontaneously, a significant minority still have dysphagia at six months. Although multiple advances have been made in the hyperacute treatment of stroke and secondary prevention, the management of dysphagia post-stroke remains a neglected area of research, and its optimal management, including diagnosis, investigation and treatment, have still to be defined.
引用
收藏
页码:399 / 411
页数:13
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