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Specific targeting of IL-6 signalling pathway: a new way to treat IBD?

被引：18
作者：
Desreumaux, P [1 ]
机构：
[1] CHU Lille, Lab Rech Malad Inflammatoires Intestinales, F-59037 Lille, France
来源：
GUT | 2000年 / 47卷 / 04期
关键词：
D O I：
10.1136/gut.47.4.465
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
引用
收藏
页码：465 / 466
页数：2
相关论文
共 12 条
  • [1] ADERKA D, 1989, J IMMUNOL, V143, P3517
  • [2] Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation:: Evidence in Crohn disease and experimental colitis in vivo
    Atreya, R
    Mudter, J
    Finotto, S
    Müllberg, J
    Jostock, T
    Wirtz, S
    Schütz, M
    Bartsch, B
    Holtmann, M
    Becker, C
    Strand, D
    Czaja, J
    Schlaak, JF
    Lehr, HA
    Autschbach, F
    Schürmann, G
    Nishimoto, N
    Yoshizaki, K
    Ito, H
    Kishimoto, T
    Galle, PR
    Rose-John, S
    Neurath, MF
    [J]. NATURE MEDICINE, 2000, 6 (05) : 583 - 588
  • [3] DEFECTIVE INFLAMMATORY RESPONSE IN INTERLEUKIN 6-DEFICIENT MICE
    FATTORI, E
    CAPPELLETTI, M
    COSTA, P
    SELLITTO, C
    CANTONI, L
    CARELLI, M
    FAGGIONI, R
    FANTUZZI, G
    GHEZZI, P
    POLI, V
    [J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1994, 180 (04) : 1243 - 1250
  • [4] EVIDENCE FOR CONTINUOUS STIMULATION OF INTERLEUKIN-6 PRODUCTION IN CROHNS-DISEASE
    GROSS, V
    ANDUS, T
    CAESAR, I
    ROTH, M
    SCHOLMERICH, J
    [J]. GASTROENTEROLOGY, 1992, 102 (02) : 514 - 519
  • [5] Ina K, 1999, J IMMUNOL, V163, P1081
  • [6] SOLUBLE INTERLEUKIN-6 RECEPTORS IN INFLAMMATORY BOWEL-DISEASE - RELATION TO CIRCULATING INTERLEUKIN-6
    MITSUYAMA, K
    TOYONAGA, A
    SASAKI, E
    ISHIDA, O
    IKEDA, H
    TSURUTA, O
    HARADA, K
    TATEISHI, H
    NISHIYAMA, T
    TANIKAWA, K
    [J]. GUT, 1995, 36 (01) : 45 - 49
  • [7] Dissection of signaling cascades through gp130 in vivo: Reciprocal roles for STAT3-and SHP2-mediated signals in immune responses
    Ohtani, T
    Ishihara, K
    Atsumi, T
    Nishida, K
    Kaneko, Y
    Miyata, T
    Itoh, S
    Narimatsu, M
    Maeda, H
    Fukada, T
    Itoh, M
    Okano, H
    Hibi, M
    Hirano, T
    [J]. IMMUNITY, 2000, 12 (01) : 95 - 105
  • [8] Interleukin-6 and soluble interleukin-6 receptor:: Direct stimulation of gp130 and hematopoiesis
    Peters, M
    Müller, AM
    Rose-John, S
    [J]. BLOOD, 1998, 92 (10) : 3495 - 3504
  • [9] Interleukin (IL)-6 directs the differentiation of IL-4-producing CD4(+) T cells
    Rincon, M
    Anguita, J
    Nakamura, T
    Fikrig, E
    Flavell, RA
    [J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1997, 185 (03) : 461 - 469
  • [10] Preliminary evaluation of safety and activity of recombinant human interleukin 11 in patients with active Crohn's disease
    Sands, BE
    Bank, S
    Sninsky, CA
    Robinson, M
    Katz, S
    Singleton, JW
    Miner, PB
    Safdi, MA
    Galandiuk, S
    Hanauer, SB
    Varilek, GW
    Buchman, AL
    Rodgers, VD
    Salzberg, B
    Cai, B
    Loewy, J
    DeBruin, MF
    Rogge, H
    Shapiro, M
    Schwertschlag, US
    [J]. GASTROENTEROLOGY, 1999, 117 (01) : 58 - 64
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