Pure substances and a new generation of CRMs for chemical industry

This article aims to link the certification of the purity of chemical substances with their possible new application in on- and off-line calibration and quality control/assurance of process control chemo- and/or biosensors. In addition, it provides an overview on the development of and concludes with different quality and certification criteria for pure compounds, matrix CRMs, and transfer material standards which are needed for on-and off-line purposes as above. It finally proposes a flow diagram for the preparation and certification of CRMs for the quality control/assurance of process control chemo- and/or biosensors by including the necessary requirements for such CRMs.