Syntheses of alkenylated carbohydrate derivatives toward the preparation of monolayers on silicon surfaces

This note describes the synthesis of different alkenylated carbohydrate derivatives suitable for direct attachment to hydrogen-terminated silicon surfaces. The derivatives were alkenylated at the C-1 position, while the remaining hydroxyl groups were protected. The development of such new carbohydrate-based sensing elements opens the access to new classes of biosensors. (C) 2004 Elsevier Ltd. All rights reserved.