Interaction between sodium hypochlorite and chlorhexidine gluconate

被引：143

作者：

Basrani, Bettina R.

Manek, Sheela

Sodhi, Rana N. S.

Fillery, Edward

Manzur, Aldo

机构：

[1] Univ Toronto, Fac Dent, Dept Endodont, Toronto, ON M5G 1G6, Canada

[2] Univ Toronto, Fac Dent, Dept Microbiol, Toronto, ON M5G 1G6, Canada

[3] Univ Toronto, Surface Interface Ontario, Dept Chem Engn & appl Chem, Toronto, ON, Canada

来源：

JOURNAL OF ENDODONTICS | 2007年 / 33卷 / 08期

关键词：

chlorhexidine; interaction; precipitate; sodium hypochlorite;

D O I：

10.1016/j.joen.2007.04.001

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

The combination of sodium hypochlorite (NaOCI) and chlorhexidine (CHX) results in the formation of a precipitate. The aim of this study was to determine the minimum concentration of NaOCI required to form a precipitate with 2.0% CHX. This was accomplished with a serial dilution technique. X-ray photon spectroscopy (XPS) and time-of-flight secondary ion mass spectrometry (TOF-SIMS) were used to qualify and quantify the precipitate. A color change and precipitate were induced in 2.0% CHX by 0.023 % and 0.19 % NaOCI, respectively. Both XPS and TOF-SIMS showed the presence of para-chloroaniline in an amount directly related to the concentration of NaOCI used. Until this precipitate is studied further, its formation should be avoided by removing the NaOCI before placing CHX into the canal.

引用

页码：966 / 969

页数：4

共 30 条

[1] Efficacy of chlorhexidine- and calcium hydroxide-containing medicaments against Enterococcus faecalis in vitro [J].