Caenorhabditis elegans operons:: Form and function

被引：98

作者：

Blumenthal, T ^{[1
]}

Gleason, KS ^{[1
]}

机构：

[1] Univ Colorado, Sch Med, Dept Biochem & Mol Genet, Denver, CO 80262 USA

来源：

NATURE REVIEWS GENETICS | 2003年 / 4卷 / 02期

关键词：

D O I：

10.1038/nrg995

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Nematodes are unusual among animals in having a substantial proportion of their genes arranged in polycistronic clusters that are similar to bacterial operons. Recently, a nearly complete database of the Caenorhabditis elegans genes that are transcribed in operons has been produced. Analysis of this database has identified the types of genes that are contained in the operons and the extent to which operons co-regulate genes of related function.

引用

页码：110 / 118

页数：9

共 42 条

[1]

Andersen JS, 2002, CURR BIOL, V12, P1, DOI 10.1016/S0960-9822(01)00650-9

[2] TRANSSPLICING AND POLYCISTRONIC TRANSCRIPTION IN CAENORHABDITIS-ELEGANS [J].

BLUMENTHAL, T .

TRENDS IN GENETICS, 1995, 11 (04) :132-136

[3]

Blumenthal T, 1998, BIOESSAYS, V20, P480, DOI 10.1002/(SICI)1521-1878(199806)20:6&lt

[4]

480::AID-BIES6&gt

[5]

3.0.CO

[6]

2-Q

[7] A global analysis of Caenorhabditis elegans operons [J].

Blumenthal, T ;

Evans, D ;

Link, CD ;

Guffanti, A ;

Lawson, D ;

Thierry-Mieg, J ;

Thierry-Mieg, D ;

Chiu, WL ;

Duke, K ;

Kiraly, M ;

Kim, SK .

NATURE, 2002, 417 (6891) :851-854

[8] Gene structure and organization in Caenorhabditis elegans [J].

Blumenthal, T ;

Spieth, J .

CURRENT OPINION IN GENETICS & DEVELOPMENT, 1996, 6 (06) :692-698

[9]

BLUMENTHAL T, 1997, C ELEGANS, V2, P117

[10]

CLARK SG, 1994, GENETICS, V137, P987

← 1 2 3 4 5 →