Proteomics: the first decade and beyond

被引：449

作者：

Patterson, SD

Aebersold, RH

机构：

[1] Celera Genom Corp, Rockville, MD 20850 USA

[2] Inst Syst Biol, Seattle, WA 98103 USA

来源：

NATURE GENETICS | 2003年 / 33卷 / Suppl 3期

关键词：

D O I：

10.1038/ng1106

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Proteomics is the systematic study of the many and diverse properties of proteins in a parallel manner with the aim of providing detailed descriptions of the structure, function and control of biological systems in health and disease. Advances in methods and technologies have catalyzed an expansion of the scope of biological studies from the reductionist biochemical analysis of single proteins to proteome-wide measurements. Proteomics and other complementary analysis methods are essential components of the emerging 'systems biology' approach that seeks to comprehensively describe biological systems through integration of diverse types of data and, in the future, to ultimately allow computational simulations of complex biological systems.

引用

页码：311 / 323

页数：13

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