PDP: protein domain parser

被引:123
作者
Alexandrov, N
Shindyalov, I
机构
[1] Ceres Inc, Malibu, CA 90265 USA
[2] Univ Calif San Diego, San Diego Supercomp Ctr, La Jolla, CA 92093 USA
关键词
D O I
10.1093/bioinformatics/btg006
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
We have developed a program for automatic identification of domains in protein three-dimensional structures. Performance of the program was assessed by three different benchmarks: (i) by comparison with the expert-curated SCOP database of structural domains; (ii) by comparison with a collection of manual domain assignments; and (iii) by comparison with a set of 55 proteins, frequently used as a benchmark for automatic domain assignment. In all these benchmarks PDP identified domains correctly in more than 80% of proteins.
引用
收藏
页码:429 / 430
页数:2
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