PDP: protein domain parser

被引：123

作者：

Alexandrov, N

Shindyalov, I

机构：

[1] Ceres Inc, Malibu, CA 90265 USA

[2] Univ Calif San Diego, San Diego Supercomp Ctr, La Jolla, CA 92093 USA

来源：

BIOINFORMATICS | 2003年 / 19卷 / 03期

关键词：

D O I：

10.1093/bioinformatics/btg006

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

We have developed a program for automatic identification of domains in protein three-dimensional structures. Performance of the program was assessed by three different benchmarks: (i) by comparison with the expert-curated SCOP database of structural domains; (ii) by comparison with a collection of manual domain assignments; and (iii) by comparison with a set of 55 proteins, frequently used as a benchmark for automatic domain assignment. In all these benchmarks PDP identified domains correctly in more than 80% of proteins.

引用

页码：429 / 430

页数：2

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