Sustained viral suppression and immune recovery in HIV type 1-infected children after 4 years of highly active antiretroviral therapy

被引：25

作者：

Fraaij, PLA

Verweel, G

van Rossum, AMC

van Lochem, EG

Schutten, M

Weemaes, CMR

Hartwig, NG

Burger, DM

de Groot, R

机构：

[1] Sophia Childrens Univ Hosp, Erasmus Med Ctr, Dept Pediat, NL-3015 GJ Rotterdam, Netherlands

[2] Erasmus MC, Dept Immunol, Rotterdam, Netherlands

[3] Erasmus MC, Dept Virol, Rotterdam, Netherlands

[4] Univ Nijmegen, Med Ctr, Ctr Infect Dis, Dept Pediat, Nijmegen, Netherlands

[5] Univ Nijmegen, Med Ctr, Ctr Infect Dis, Dept Clin Pharm, Nijmegen, Netherlands

来源：

CLINICAL INFECTIOUS DISEASES | 2005年 / 40卷 / 04期

关键词：

D O I：

10.1086/427696

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We report the data from a long-term study of 31 human immunodeficiency virus type 1 (HIV-1)-infected children who were treated with highly active antiretroviral therapy. A high proportion of the children had undetectable HIV-1 RNA levels. CD4(+) T cell counts recovered and remained stable. Adverse events were observed frequently but were mostly mild.

引用

页码：604 / 608

页数：5

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