Acute interstitial nephritis associated with atazanavir, a new protease inhibitor

被引：62

作者：

Brewster, UC ^{[1
]}

Perazella, MA ^{[1
]}

机构：

[1] Yale Univ, Sch Med, Nephrol Sect, Renal Fellowship Program, New Haven, CT 06520 USA

来源：

AMERICAN JOURNAL OF KIDNEY DISEASES | 2004年 / 44卷 / 05期

关键词：

atazanavir; acute interstitial nephritis (AIN); acute renal failure (ARF); human immunodeficiency virus (HIV) infection;

D O I：

10.1053/j.ajkd.2004.07.017

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Atazanavir is a new human immunodeficiency virus 1 protease inhibitor that has a favorable side-effect profile and is available in once-daily dosing. We report the case of a young man with human immunodeficiency virus infection who developed acute renal failure after therapy with this drug. Renal biopsy showed acute interstitial nephritis. This is the first report of acute interstitial nephritis from atazanavir.

引用

页码：E81 / E84

页数：7

共 8 条

[1]

BERNS JS, 1991, J AM SOC NEPHROL, V1, P1061

[2] Acute tubulointerstitial nephritis associated with celecoxib [J].

Brewster, UC ;

Perazella, MA .

NEPHROLOGY DIALYSIS TRANSPLANTATION, 2004, 19 (04) :1017-1018

[3] Atazanavir [J].

Goldsmith, DR ;

Perry, CM .

DRUGS, 2003, 63 (16) :1679-1693

[4] Dose-ranging, randomized, clinical trial of atazanavir with lamivudine and stavudine in anti retroviral-naive subjects: 48-week results [J].

Murphy, RL ;

Sanne, I ;

Cahn, P ;

Phanuphak, P ;

Percival, L ;

Kelleher, T ;

Giordano, M .

AIDS, 2003, 17 (18) :2603-2614

[5] Acute renal failure in HIV-infected patients: A brief review of common causes [J].

Perazella, MA .

AMERICAN JOURNAL OF THE MEDICAL SCIENCES, 2000, 319 (06) :385-391

[6]

Rao TKS, 1998, SEMIN NEPHROL, V18, P378

[7]

RAO TKS, 1995, AM J KIDNEY DIS, V25, P390

[8] Antiretroviral treatment for adult HIV infection in 2002 - Updated recommendations of the international AIDS Society-USA panel [J].

Yeni, PG ;

Hammer, SM ;

Carpenter, CCJ ;

Cooper, DA ;

Fischl, MA ;

Gatell, JM ;

Gazzard, BG ;

Hirsch, MS ;

Jacobsen, DM ;

Katzenstein, DA ;

Montaner, JSG ;

Richman, DD ;

Saag, MS ;

Schechter, M ;

Schooley, RT ;

Thompson, MA ;

Vella, S ;

Volberding, PA .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2002, 288 (02) :222-235

← 1 →