Taste disorders in cancer patients: Pathogenesis, and approach to assessment and management

被引：119

作者：

Epstein, Joel B. ^{[1
,2
]}

Barasch, Andrei ^{[3
]}

机构：

[1] Univ Illinois, Coll Dent, Dept Oral Med & Diagnost Sci, Chicago, IL 60607 USA

[2] Univ Illinois, Coll Med, Chicago Canc Ctr, Dept Otolaryngol Head & Neck Surg, Chicago, IL USA

[3] Univ Alabama Birmingham, Dept Gen Dent Sci, Birmingham, AL USA

来源：

ORAL ONCOLOGY | 2010年 / 46卷 / 02期

关键词：

Taste; Dysgeusia; Oncology; Quality of life; Cancer; QUALITY-OF-LIFE; BONE-MARROW TRANSPLANTATION; NECK-CANCER; GUSTATORY FUNCTION; PHASE-III; INTRAVENOUS AMIFOSTINE; MAMMALIAN TASTE; ZINC-SULFATE; HEAD; RADIOTHERAPY;

D O I：

10.1016/j.oraloncology.2009.11.008

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 [肿瘤学];

摘要：

Taste dysfunction in cancer patients impacts quality of life and impairs oral intake, which may have broader implications consisting of weight loss and nutritional compromise. These consequences may in turn affect broad symptom clusters including tissue healing, energy levels and mood. Patient evaluation and management should include a complete patient history and examination, and may require special tests. Patient-reported outcomes together with taste and smell testing are often necessary for diagnosis and management of taste disorders. Understanding, prevention and management of taste disorders in cancer patients requires continuing study. Current practice and recommendations are based on limited evidence. Due to its potentially significant impact on quality of life during and following cytotoxic therapy, and considering the increase in cancer survivorship, further research on this topic is imperative. Crown Copyright (C) 2009 Published by Elsevier Ltd. All rights reserved.

引用

页码：77 / 81

页数：5

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