Torsades de pointes and self-terminating ventricular fibrillation in a prescription methadone user

被引：21

作者：

Atkinson, D. ^{[1
]}

Dunne, A. ^{[1
]}

Parker, M. ^{[1
]}

机构：

[1] Manchester Royal Infirm, Crit Care Unit, Manchester M13 9WL, Lancs, England

来源：

ANAESTHESIA | 2007年 / 62卷 / 09期

关键词：

LONG-QT SYNDROME; CLINICAL-FEATURES; PROLONGATION; PATIENT; SYNCOPE;

D O I：

10.1111/j.1365-2044.2007.05129.x

中图分类号：

R614 [麻醉学];

学科分类号：

100217 [麻醉学];

摘要：

Methadone is known to prolong the QT interval and precipitate torsades de pointes. A 54-year-old prescription methadone user with hypokalaemia was referred to Critical Care with acute confusion and respiratory distress. Alcohol withdrawal was the presumed precipitant. The real precipitant only became evident on analysis of a 24-h ECG (Holter monitor) attached to the patient at the time. The patient had suffered prolonged (10 min) ventricular arrhythmias including torsades de pointes and self-terminating ventricular fibrillation. The patient made a full recovery. Risk factors for acquired long QT syndrome and the treatment of torsades de pointes are discussed.

引用

页码：952 / 955

页数：4

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