Culture-independent analysis of vaginal microflora:: The unrecognized association of Atopobium vaginae with bacterial vaginosis

被引:82
作者
Verstraelen, H
Verhelst, R
Claeys, G
Temmerman, M
Vaneechoutte, M
机构
[1] State Univ Ghent, Fac Med & Hlth Sci, Dept Obstet & Gynaecol, B-9000 Ghent, Belgium
[2] State Univ Ghent, Dept Clin Chem, B-9000 Ghent, Belgium
[3] State Univ Ghent, Dept Microbiol & Immunol, B-9000 Ghent, Belgium
关键词
bacterial vaginosis; Atopobium vaginae; 16S rDNA amplification; vaginal flora;
D O I
10.1016/j.ajog.2004.04.013
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Although the pathogenesis of bacterial vaginosis remains elusive, a few microorganisms, such as Gardnerella vaginalis, are considered markers on Gram stain or culture. Culture-independent analysis of vaginal microflora using 16S rDNA cloning and sequencing of total bacterial. communities reveals the gram-positive Atopobium vaginae as a predominant species in disturbed vaginal flora. (C) 2004 Elsevier Inc. All rights reserved.
引用
收藏
页码:1130 / 1132
页数:3
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