Extremes of Unexplained Variation as a Phenotype An Efficient Approach for Genome-Wide Association Studies of Cardiovascular Disease

被引:45
作者
Lanktree, Matthew B. [2 ]
Hegele, Robert A. [1 ,2 ]
Schork, Nicholas J. [4 ]
Spence, J. David [3 ]
机构
[1] Univ Western Ontario, Robarts Res Inst, Blackburn Cardiovasc Genet Lab, Dept Med, London, ON N6A 5K8, Canada
[2] Univ Western Ontario, Robarts Res Inst, Dept Biochem, London, ON N6A 5K8, Canada
[3] Univ Western Ontario, Robarts Res Inst, Stroke Prevent & Atherosclerosis Res Ctr, London, ON N6A 5K8, Canada
[4] Scripps Translat Sci Inst, La Jolla, CA USA
关键词
cardiovascular disease; atherosclerosis; risk factors; stroke; genome-wide association studies; ultrasound; QUANTITATIVE-TRAIT LOCI; LINKAGE DISEQUILIBRIUM; CAROTID ATHEROSCLEROSIS; BLOOD-PRESSURE; HEART-DISEASE; RISK-FACTORS; POWER; POPULATION; SAMPLES; VARIANTS;
D O I
10.1161/CIRCGENETICS.109.934505
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
[No abstract available]
引用
收藏
页码:215 / 221
页数:7
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