Incidence of variant Creutzfeldt-Jakob disease in the UK

被引:43
作者
Andrews, NJ
Farrington, CP
Cousens, SN
Smith, PG
Ward, H
Knight, RSG
Ironside, JW
Will, RG [1 ]
机构
[1] Western Gen Hosp, Natl CJD Surveillance Unit, Edinburgh EH4 2XU, Midlothian, Scotland
[2] PHLS, Stat Unit, London, England
[3] Open Univ, Dept Stat, Milton Keynes MK7 6AA, Bucks, England
[4] London Sch Hyg & Trop Med, Dept Infect & Trop Dis, London WC1, England
关键词
D O I
10.1016/S0140-6736(00)02559-9
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The number of deaths from variant CJD (vCJD) in the UK increased in the last quarter of 1998, although numbers were lower in subsequent quarters. We analysed the numbers of definite and probable (living and dead) vCJD cases since 1994 to assess trends in incidence. We estimated that the number of onsets increased by 23% per year for 1994-2000 (p=0.004), and that deaths increased by 33% for 1995-2000 (p=0.005). The absolute number of cases in the UK is still low, but such an increase should be a matter of concern.
引用
收藏
页码:481 / 482
页数:2
相关论文
共 5 条
  • [1] Transmissions to mice indicate that 'new variant' CJD is caused by the BSE agent
    Bruce, ME
    Will, RG
    Ironside, JW
    McConnell, I
    Drummond, D
    Suttie, A
    McCardle, L
    Chree, A
    Hope, J
    Birkett, C
    Cousens, S
    Fraser, H
    Bostock, CJ
    [J]. NATURE, 1997, 389 (6650) : 498 - 501
  • [2] The same prion strain causes vCJD and BSE
    Hill, AF
    Desbruslais, M
    Joiner, S
    Sidle, KCL
    Gowland, I
    Collinge, J
    Doey, LJ
    Lantos, P
    [J]. NATURE, 1997, 389 (6650) : 448 - 450
  • [3] *NAT CJD SURV UN L, 1999, CREUTZF DIS SURV UK
  • [4] Will RG, 2000, ANN NEUROL, V47, P575
  • [5] Deaths from variant Creutzfeldt-Jakob disease
    Will, RG
    Cousens, SN
    Farrington, CP
    Smith, PG
    Knight, RSG
    Ironside, JW
    [J]. LANCET, 1999, 353 (9157) : 979 - 979