Animal transgenesis: recent data and perspectives

被引：8

作者：

Houdebine, LM ^{[1
]}

机构：

[1] INRA, F-78352 Jouy En Josas, France

来源：

BIOCHIMIE | 2002年 / 84卷 / 11期

关键词：

transgenic animal; generation; applications;

D O I：

10.1016/S0300-9084(02)00012-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Gene transfer to generate transgenic animals is used more and more to study gene regulation and function. It is also an essential tool to prepare pharmaceuticals or pig organs for transplantation to humans. It is also expected to be a potent way to generate farm animals having traits that cannot emerge by conventional selection. During the last few years, the different techniques to generate transgenic animals and obtain a well-controlled expression of the transgenes have been quite significantly improved. This paper is a brief summary of the most recent relevant data in this field. (C) 2002 Editions scientifiques et medicales Elsevier SAS and Societe francaise de biochimie et biologie moleculaire. All tights reserved.

引用

收藏

页码：1137 / 1141

页数：5

相关论文

共 39 条

[1] Coping with kinetic and thermodynamic barriers: RMCE, an efficient strategy for the targeted integration of transgenes [J].

Baer, A ;

Bode, J .

CURRENT OPINION IN BIOTECHNOLOGY, 2001, 12 (05) :473-480

[2] A system for stable expression of short interfering RNAs in mammalian cells [J].

Brummelkamp, TR ;

Bernards, R ;

Agami, R .

SCIENCE, 2002, 296 (5567) :550-553

[3] Transgenic cattle produced by reverse-transcribed gene transfer in oocytes [J].

Chan, AWS ;

Homan, EJ ;

Ballou, LU ;

Burns, JC ;

Bremel, RD .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (24) :14028-14033

[4] Transgenic monkeys produced by retroviral gene transfer into mature oocytes [J].

Chan, AWS ;

Chong, KY ;

Martinovich, C ;

Simerly, C ;

Schatten, G .

SCIENCE, 2001, 291 (5502) :309-312

[5] Cloned rabbits produced by nuclear transfer from adult somatic cells [J].

Chesné, P ;

Adenot, PG ;

Viglietta, C ;

Baratte, M ;

Boulanger, L ;

Renard, JP .

NATURE BIOTECHNOLOGY, 2002, 20 (04) :366-369

[6] Targeted disruption of the α1,3-galactosyltransferase gene in cloned pigs [J].

Dai, YF ;

Vaught, TD ;

Boone, J ;

Chen, SH ;

Phelps, CJ ;

Ball, S ;

Monahan, JA ;

Jobst, PM ;

McCreath, KJ ;

Lamborn, AE ;

Cowell-Lucero, JL ;

Wells, KD ;

Colman, A ;

Polejaeva, IA ;

Ayares, DL .

NATURE BIOTECHNOLOGY, 2002, 20 (03) :251-255

[7] Deletion of the α(1,3)galactosyl transferase (GGTA1) gene and the prion protein (PrP) gene in sheep [J].

Denning, C ;

Burl, S ;

Ainslie, A ;

Bracken, J ;

Dinnyes, A ;

Fletcher, J ;

King, T ;

Ritchie, M ;

Ritchie, WA ;

Rollo, M ;

de Sousa, P ;

Travers, A ;

Wilmut, I ;

Clark, AJ .

NATURE BIOTECHNOLOGY, 2001, 19 (06) :559-562

[8] Mammalian germ-line transgenesis by transposition [J].

Dupuy, AJ ;

Clark, K ;

Carlson, CM ;

Fritz, S ;

Davidson, AE ;

Markley, KM ;

Finley, K ;

Fletcher, CF ;

Ekker, SC ;

Hackett, PB ;

Horn, S ;

Largaespada, DA .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (07) :4495-4499

[9] Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells [J].

Elbashir, SM ;

Harborth, J ;

Lendeckel, W ;

Yalcin, A ;

Weber, K ;

Tuschl, T .

NATURE, 2001, 411 (6836) :494-498

[10] Site-specific chromosomal integration in mammalian cells: Highly efficient CRE recombinase-mediated cassette exchange [J].

Feng, YQ ;

Seibler, J ;

Alami, R ;

Eisen, A ;

Westerman, KA ;

Leboulch, P ;

Fiering, S ;

Bouhassira, EE .

JOURNAL OF MOLECULAR BIOLOGY, 1999, 292 (04) :779-785

← 1 2 3 4 →