Stimulatory effect of cyanidin 3-glycosides on the regeneration of rhodopsin

被引：184

作者：

Matsumoto, H

Nakamura, Y

Tachibanaki, S

Kawamura, S

Hirayama, M

机构：

[1] Meiji Seika Kaisha Ltd, Hlth & Biosci Labs, Sakado, Saitama 3500289, Japan

[2] Osaka Univ, Grad Sch Sci, Dept Biol, Toyonaka, Osaka 5600043, Japan

来源：

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY | 2003年 / 51卷 / 12期

关键词：

rhodopsin; regeneration; 11-cis-retinal; anthocyanin; black currant;

D O I：

10.1021/jf034132y

中图分类号：

S [农业科学];

学科分类号：

09 ;

摘要：

Anthocyanins have been suggested to improve visual functions. This study examined the effect of four anthocyanins in black currant fruits on the regeneration of rhodopsin using frog rod outer segment (ROS) membranes. Cyanidin 3-glycosides, glucoside and rutinoside, stimulated the regeneration, but the corresponding delphinidins showed no significant effect. The formation of a regeneration intermediate was suggested to be accelerated by cyanidin 3-rutinoside. Their effects on the cGMP-phosphodiesterase activity in the ROS membranes were also investigated but found to be negligible. It was concluded that the major effect of anthocyanins in rod photoreceptors is on the regeneration of rhodopsin.

引用

页码：3560 / 3563

页数：4

共 21 条

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