Towards the directed evolution of hybrid catalysts

被引：82

作者：

Reetz, MT ^{[1
]}

Rentzsch, M ^{[1
]}

Pletsch, A ^{[1
]}

Maywald, M ^{[1
]}

机构：

[1] Max Planck Inst Kohlenforsch, D-45470 Mulheim, Germany

来源：

CHIMIA | 2002年 / 56卷 / 12期

关键词：

chemical modification; directed evolution; enzymes; hybrid catalysts; transition metal catalysis;

D O I：

10.2533/000942902777679920

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The first step in applying the recently proposed concept concerning the application of directed evolution to the creation of selective hybrid catalysts is described, specifically the covalent attachment of Mn-salen moieties and of Cu-, Pd-, and Rh-complexes of dipyridine derivatives as well as the implantation of a diphosphine moiety in a protein, future steps being cycles of mutagenesis/screening.

引用

页码：721 / 723

页数：3

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