New picrotoxinin-type and dendrobine-type sesquiterpenoids from Dendrobium Snowflake 'Red Star'

被引:70
作者
Morita, H [1 ]
Fujiwara, M [1 ]
Yoshida, N [1 ]
Kobayashi, J [1 ]
机构
[1] Hokkaido Univ, Grad Sch Pharmaceut Sci, Sapporo, Hokkaido 0600812, Japan
关键词
sesquiterpenoids; alkaloids; Dendrobium; Orchidaceae;
D O I
10.1016/S0040-4020(00)00530-5
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Two new picrotoxinin-type sesquiterpenes, flakinins A (1) and B (2), and three new dendrobine-type sesquiterpene alkaloids, mubironines A (3), B (4), and C (5), have been isolated from the whole plants of Dendrobium Snowflake 'Red Star' (Orchidaceae). Their stereostructures were elucidated by 2D NMR data and chemical means. (C) 2000 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:5801 / 5805
页数:5
相关论文
共 7 条
[1]   STUDIES ON ORCHIDACEAE ALKALOIDS .28. ABSOLUTE CONFIGURATION OF DENDROBINE ALKALOIDS [J].
BEHR, D ;
LEANDER, K .
ACTA CHEMICA SCANDINAVICA, 1972, 26 (08) :3196-3202
[2]   Molecular biology of insect neuronal GABA receptors [J].
Hosie, AM ;
Aronstein, K ;
Sattelle, DB ;
ffrenchConstant, RH .
TRENDS IN NEUROSCIENCES, 1997, 20 (12) :578-583
[3]  
Hsu H., 1986, ORIENTAL MAT MED CON, P582
[4]   TAXUSPINES-A-C, NEW TAXOIDS FROM JAPANESE YEW TAXUS-CUSPIDATA INHIBITING DRUG TRANSPORT ACTIVITY OF P-GLYCOPROTEIN IN MULTIDRUG-RESISTANT CELLS [J].
KOBAYASHI, J ;
OGIWARA, A ;
HOSOYAMA, H ;
SHIGEMORI, H ;
YOSHIDA, N ;
SASAKI, T ;
LI, Y ;
IWASAKI, S ;
NAITO, M ;
TSURUO, T .
TETRAHEDRON, 1994, 50 (25) :7401-7416
[5]   Daphnezomines A and B, novel alkaloids with an aza-adamantane core from Daphniphyllum humile [J].
Morita, H ;
Yoshida, N ;
Kobayashi, J .
JOURNAL OF ORGANIC CHEMISTRY, 1999, 64 (19) :7208-7212
[6]   PICROTOXININ AND RELATED SUBSTANCES [J].
PORTER, LA .
CHEMICAL REVIEWS, 1967, 67 (04) :441-+
[7]   DENDROBINE AND 3-HYDROXY-2-OXODENDROBINE FROM DENDROBIUM-NOBILE [J].
WANG, HK ;
WANG, XK ;
ZHAO, TF ;
CHE, CT .
JOURNAL OF NATURAL PRODUCTS, 1985, 48 (05) :796-801