Structural neurology: Are seeds at the root of neuronal degeneration?

被引：149

作者：

Lansbury, PT ^{[1
]}

机构：

[1] Harvard Univ, Brigham & Womens Hosp, Sch Med, Ctr Neurol Dis,Dept Neurol, Boston, MA 02115 USA

来源：

NEURON | 1997年 / 19卷 / 06期

关键词：

D O I：

10.1016/S0896-6273(00)80406-7

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

[No abstract available]

引用

页码：1151 / 1154

页数：4

共 15 条

[1] Aggregates of scrapie-associated prion protein induce the cell-free conversion of protease-sensitive prion protein to the protease-resistant state [J].

Caughey, B ;

Kocisko, DA ;

Raymond, GJ ;

Lansbury, PT .

CHEMISTRY & BIOLOGY, 1995, 2 (12) :807-817

[2] Allelic origin of the abnormal prion protein isoform in familial prion diseases [J].

Chen, SG ;

Parchi, P ;

Brown, P ;

Capellari, S ;

Zou, WQ ;

Cochran, EJ ;

VnencakJones, CL ;

Julien, J ;

Vital, C ;

Mikol, J ;

Lugaresi, E ;

AutilioGambetti, L ;

Gambetti, P .

NATURE MEDICINE, 1997, 3 (09) :1009-1015

[3] Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation [J].

Davies, SW ;

Turmaine, M ;

Cozens, BA ;

DiFiglia, M ;

Sharp, AH ;

Ross, CA ;

Scherzinger, E ;

Wanker, EE ;

Mangiarini, L ;

Bates, GP .

CELL, 1997, 90 (03) :537-548

[4] Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain [J].

DiFiglia, M ;

Sapp, E ;

Chase, KO ;

Davies, SW ;

Bates, GP ;

Vonsattel, JP ;

Aronin, N .

SCIENCE, 1997, 277 (5334) :1990-1993

[5] THE BIOPHYSICS OF SICKLE-CELL HYDROXYUREA THERAPY [J].

EATON, WA ;

HOFRICHTER, J .

SCIENCE, 1995, 268 (5214) :1142-1143

[6] Models of amyloid seeding in Alzheimier's disease and scrapie: Mechanistic truths and physiological consequences of the time-dependent solubility of amyloid proteins [J].

Harper, JD ;

Lansbury, PT .

ANNUAL REVIEW OF BIOCHEMISTRY, 1997, 66 :385-407

[7] Dementia with Lewy bodies [J].

Kosaka, K ;

Iseki, E .

CURRENT OPINION IN NEUROLOGY, 1996, 9 (04) :271-275

[8] Intranuclear inclusions of expanded polyglutamine protein in spinocerebellar ataxia type 3 [J].

Paulson, HL ;

Perez, MK ;

Trottier, Y ;

Trojanowski, JQ ;

Subramony, SH ;

Das, SS ;

Vig, P ;

Mandel, JL ;

Fischbeck, KH ;

Pittman, RN .

NEURON, 1997, 19 (02) :333-344

[9] Mutation in the alpha-synuclein gene identified in families with Parkinson's disease [J].

Polymeropoulos, MH ;

Lavedan, C ;

Leroy, E ;

Ide, SE ;

Dehejia, A ;

Dutra, A ;

Pike, B ;

Root, H ;

Rubenstein, J ;

Boyer, R ;

Stenroos, ES ;

Chandrasekharappa, S ;

Athanassiadou, A ;

Papapetropoulos, T ;

Johnson, WG ;

Lazzarini, AM ;

Duvoisin, RC ;

DiIorio, G ;

Golbe, LI ;

Nussbaum, RL .

SCIENCE, 1997, 276 (5321) :2045-2047

[10] Prion diseases and the BSE crisis [J].

Prusiner, SB .

SCIENCE, 1997, 278 (5336) :245-251

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