Antigen-driven clonal T cell expansion in disorders of hematopoiesis

被引:15
作者
Kanchan, K
Loughran, TP
机构
[1] Univ S Florida, H Lee Moffit Canc Ctr & Res Inst, Hematol Malignancies Program, Coll Med, Tampa, FL 33612 USA
[2] Univ S Florida, Dept Interdisciplinary Oncol, Coll Med, Tampa, FL 33612 USA
[3] Univ S Florida, Dept Med, Coll Med, Tampa, FL 33612 USA
关键词
aplastic anemia; myelodysplastic syndrome; LGL leukemia; cytotoxic T lymphocytes;
D O I
10.1016/S0145-2126(02)00270-9
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Patients with myelodysplastic syndrome, aplastic anemia, and LGL leukemia may have overlapping clinical features. This commentary highlights a possible common pathogenetic mechanism of antigen-driven cytotoxic T lymphocytes mediating hematopoietic failure. (C) 2002 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:291 / 292
页数:2
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