Three tyrosinase inhibitors and antioxidant compounds from Salsola foetida

被引：56

作者：

Khan, KM ^{[1
]}

Maharvi, GM ^{[1
]}

Abbaskhan, A ^{[1
]}

Hayat, S ^{[1
]}

Khan, MTH ^{[1
]}

Makhmoor, T ^{[1
]}

Choudhary, MI ^{[1
]}

Shaheen, F ^{[1
]}

Att-ur-Raham ^{[1
]}

机构：

[1] Univ Karachi, Int Ctr Chem Sci, HEJ Res Inst Chem, Karachi 75270, Pakistan

来源：

HELVETICA CHIMICA ACTA | 2003年 / 86卷 / 02期

关键词：

D O I：

10.1002/hlca.200390045

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Phytochemical investigation on the whole plant of Salsola foetida resulted in the isolation of three new phenolic compounds 1, 2, and 3, which exhibit tyrosinase inhibition with moderate antioxidant activity. Compounds 1-3 inhibited tyrosinase with IC50. 2.61, 1.85, and 0.40 muM, while exhibiting DPPH radical scavenging activity with IC50 383, 427 and 378 muM, respectively. The structures of 1, 2, and 3 were determined by modern spectroscopic techniques.

引用

页码：457 / 464

页数：8