Vaccine delivery methods using viral vectors

被引：83

作者：

Brave, Andreas

Ljungberg, Karl

Wahren, Britta

Liu, Margaret A.

机构：

[1] Karolinska Inst, Swedish Inst Infect Dis Control, S-17182 Stockholm, Sweden

[2] Karolinska Inst, Dept Microbiol Tumor & Cell Biol, S-17182 Stockholm, Sweden

[3] Univ N Carolina, Carolina Vaccine Inst, Chapel Hill, NC 27599 USA

来源：

MOLECULAR PHARMACEUTICS | 2007年 / 4卷 / 01期

关键词：

DNA vaccines; adenovirus; adeno-associated virus; poxvirus; canarypox; MVA; vesicular stomatitis virus; alphavirus; measles; vaccine strategies; preexisting immunity; prime-boost; VESICULAR STOMATITIS-VIRUS; RECOMBINANT ADENOASSOCIATED VIRUS; SIMIAN-IMMUNODEFICIENCY-VIRUS; EQUINE ENCEPHALITIS-VIRUS; WEST-NILE-VIRUS; T-CELL RESPONSES; ALPHAVIRUS REPLICON PARTICLES; MULTIPROTEIN DNA/MVA VACCINE; SITE-SPECIFIC INTEGRATION; IMMUNE-RESPONSES;

D O I：

10.1021/mp060098+

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Viral vectors have different capabilities as gene delivery vehicles for vaccines and immunotherapeutics. This review discusses selected viral vector systems and plasmid DNA and provides an overview of their specific characteristics, strengths, and limitations. The features, modes of viral entry and replication, expression of heterologous proteins, issues related to both preexisting and heterologous immunity, and vaccine strategies are discussed for the different vectors. Comparisons of the features and capabilities of the vectors are provided.

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收藏

页码：18 / 32

页数：15

相关论文

共 136 条

[1] Dendritic cells acquire antigen from apoptotic cells and induce class I restricted CTLs [J].

Albert, ML ;

Sauter, B ;

Bhardwaj, N .

NATURE, 1998, 392 (6671) :86-89

[2] Control of a mucosal challenge and prevention of AIDS by a multiprotein DNA/MVA vaccine [J].

Amara, RR ;

Villinger, F ;

Altman, JD ;

Lydy, SL ;

O'Neil, SP ;

Staprans, SI ;

Montefiori, DC ;

Xu, Y ;

Herndon, JG ;

Wyatt, LS ;

Candido, MA ;

Kozyr, NL ;

Earl, PL ;

Smith, JM ;

Ma, HL ;

Grimm, BD ;

Hulsey, ML ;

McClure, HM ;

McNicholl, JM ;

Moss, B ;

Robinson, HL .

VACCINE, 2002, 20 (15) :1949-1955

[3] Control of a mucosal challenge and prevention of AIDS by a multiprotein DNA/MVA vaccine [J].

Amara, RR ;

Villinger, F ;

Altman, JD ;

Lydy, SL ;

O'Neil, SP ;

Staprans, SI ;

Montefiori, DC ;

Xu, Y ;

Herndon, JG ;

Wyatt, LS ;

Candido, MA ;

Kozyr, NL ;

Earl, PL ;

Smith, JM ;

Ma, HL ;

Grimm, BD ;

Hulsey, ML ;

Miller, J ;

McClure, HM ;

McNicholl, JM ;

Moss, B ;

Robinson, HL .

SCIENCE, 2001, 292 (5514) :69-74

[4] ENGINEERING POLIOVIRUS AS A VACCINE VECTOR FOR THE EXPRESSION OF DIVERSE ANTIGENS [J].

ANDINO, R ;

SILVERA, D ;

SUGGETT, SD ;

ACHACOSO, PL ;

MILLER, CJ ;

BALTIMORE, D ;

FEINBERG, MB .

SCIENCE, 1994, 265 (5177) :1448-1451

[5] ChimeriVax-West Nile virus live-attenuated vaccine: Preclinical evaluation of safety, immunogenicity, and efficacy [J].

Arroyo, J ;

Miller, C ;

Catalan, J ;

Myers, GA ;

Ratterree, MS ;

Trent, DW ;

Monath, TP .

JOURNAL OF VIROLOGY, 2004, 78 (22) :12497-12507

[6] Infectious entry pathway of adeno-associated virus and adeno-associated virus vectors [J].

Bartlett, JS ;

Wilcher, R ;

Samulski, RJ .

JOURNAL OF VIROLOGY, 2000, 74 (06) :2777-2785

[7]

BAUM S, 1995, MANDELL DOUGLAS BENN, V2, P1382

[8] Induction of immune responses to HIV-1 by canarypox virus (ALVAC) HIV-1 and gp120 SF-2 recombinant vaccines in uninfected volunteers [J].

Belshe, RB ;

Gorse, GJ ;

Mulligan, MJ ;

Evans, TG ;

Keefer, MC ;

Excler, JL ;

Duliege, AM ;

Tartaglia, J ;

Cox, WI ;

McNamara, J ;

Hwang, KL ;

Bradney, A ;

Montefiori, D ;

Weinhold, KJ .

AIDS, 1998, 12 (18) :2407-2415

[9] Isolation of a common receptor for coxsackie B viruses and adenoviruses 2 and 5 [J].

Bergelson, JM ;

Cunningham, JA ;

Droguett, G ;

KurtJones, EA ;

Krithivas, A ;

Hong, JS ;

Horwitz, MS ;

Crowell, RL ;

Finberg, RW .

SCIENCE, 1997, 275 (5304) :1320-1323

[10] Outcome of immunization of cynomolgus monkeys with recombinant Semliki Forest virus encoding human immunodeficiency virus type 1 envelope protein and challenge with a high dose of SHIV-4 virus [J].

Berglund, P ;

QuesadaRolander, M ;

Putkonen, P ;

Biberfeld, G ;

Thorstensson, R ;

Liljestrom, P .

AIDS RESEARCH AND HUMAN RETROVIRUSES, 1997, 13 (17) :1487-1495

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