Gestational diabetes mellitus

被引:713
作者
Buchanan, TA
Xiang, AH
机构
[1] Univ So Calif, Keck Sch Med, Dept Med, Los Angeles, CA USA
[2] Univ So Calif, Keck Sch Med, Dept Obstet & Gynecol, Los Angeles, CA USA
[3] Univ So Calif, Keck Sch Med, Dept Physiol & Biophys, Los Angeles, CA USA
[4] Univ So Calif, Keck Sch Med, Dept Prevent Med, Los Angeles, CA USA
关键词
D O I
10.1172/JCI200524531
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Gestational diabetes mellitus (GDM) is defined as glucose intolerance of various degrees that is first detected during pregnancy. GDM is detected through the screening of pregnant women W for clinical risk factors and, among at-risk women, testing for abnormal glucose tolerance that is usually, but not invariably, mild and asymptomatic. GDM appears to result from the same broad spectrum of physiological and genetic abnormalities that characterize diabetes outside of pregnancy. indeed, women with GDM are at high risk for having or developing diabetes when they are not pregnant. Thus, GDM provides a unique opportunity to study the early pathogenesis of diabetes and to develop interventions to prevent the disease.
引用
收藏
页码:485 / 491
页数:7
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