Steroid estrogens, conjugated estrogens and estrogenic activity in farm dairy shed effluents

被引：95

作者：

Gadd, Jennifer B. ^{[1
]}

Tremblay, Louis A. ^{[2
]}

Northcott, Grant L. ^{[3
]}

机构：

[1] Univ Canterbury, Dept Chem, Christchurch 8140, New Zealand

[2] Landcare Res, Lincoln, New Zealand

[3] Plant & Food Res, Hamilton 3240, New Zealand

来源：

ENVIRONMENTAL POLLUTION | 2010年 / 158卷 / 03期

关键词：

Estrogen; Dairy effluent; Agricultural wastes; Endocrine disruptors; E-SCREEN ASSAY; MASS-SPECTROMETRY; MUNICIPAL SEWAGE; NEW-ZEALAND; UNITED-KINGDOM; CHEMICALS; HORMONES; MANURE; PREGNANCY; IDENTIFICATION;

D O I：

10.1016/j.envpol.2009.10.015

中图分类号：

X [环境科学、安全科学];

学科分类号：

083001 [环境科学];

摘要：

Agricultural wastes are a source of steroid estrogens and, if present, conjugated estrogens may add to the estrogen load released to soil and aquatic environments Dairy shed effluent samples were collected from 18 farms for analysis of steroid estrogens by GC-MS, conjugated estrogens by LC-MS-MS, and estrogenic activity by E-screen in vitro bioassay. 17 alpha-estradiol was found at highest concentrations (median 730 ng l(-1)), followed by estrone (100 ng l(-1)) and 17 beta-estradiol (24 ng l(-1)) Conjugated estrogens (estrone-3-sulfate,17 alpha-estradiol-3-sulfate and 17 beta-estradiol-3,17-disulfate) were measured in most samples (12-320 ng l(-1)) Median estrogenic activity was 46 ng l(-1) 17 beta-estradiol equivalents Conjugated estrogens contributed up to 22% of the total estrogen load from dairy farming, demonstrating their significance. Steroid estrogens dominated overall estrogenic activity measured in the samples Significantly, 17 alpha-estradiol contributed 25% of overall activity. despite potency 2% that of 17 beta-estradiol, highlighting the importance in environmental risk assessments of this previously neglected compound (C) 2009 Elsevier Ltd. All nghts reserved

引用

页码：730 / 736

页数：7

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