Diurnal blood pressure variation and sympathetic activity

被引:87
作者
Grassi, Guido [1 ,2 ]
Bombelli, Michele [1 ]
Seravalle, Gino [1 ,2 ]
Dell'Oro, Raffaella [1 ]
Quarti-Trevano, Fosca [1 ]
机构
[1] Univ Milano Bicocca, Osped San Gerardo, Med Clin, I-20052 Milan, Italy
[2] Ist Auxol Italiano, Milan, Italy
关键词
dipping profile; masked hypertension; sympathetic nervous system; white-coat hypertension; 24-h blood pressure; WHITE-COAT HYPERTENSION; EXAGGERATED MORNING SURGE; HEART-RATE VARIABILITIES; OBSTRUCTIVE SLEEP-APNEA; NERVOUS-SYSTEM; CEREBROVASCULAR-DISEASE; POSSIBLE DIFFERENCE; EXTREME DIPPERS; ORGAN DAMAGE; NOREPINEPHRINE;
D O I
10.1038/hr.2010.26
中图分类号
R6 [外科学];
学科分类号
100210 [外科学];
摘要
Blood pressure changes occurring over a 24-h period are under behavioral, humoral and reflex regulation. The sympathetic nervous system modulates blood pressure variation by affecting cardiac output and peripheral vascular resistance. This paper reviews evidence for the relationship between adrenergic neural drive and blood pressure as measured by direct and indirect approaches. This paper also reviews the sympathetic activity associated with increased 'in-office' and 'out-of-office' blood pressure, that is, the white-coat and the masked-hypertensive states. Finally, this paper examines altered neuroadrenergic influences on nocturnal blood pressure reduction and blood pressure variability. Hypertension Research (2010) 33, 381-385; doi: 10.1038/hr.2010.26; published online 5 March 2010
引用
收藏
页码:381 / 385
页数:5
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