Antihypertensive medication use by recently diagnosed hypertensive Canadians

被引:28
作者
Ineke Neutel, C.
Campbell, Norm R. C.
机构
[1] Publ Hlth Agcy Canada, Ottawa, ON, Canada
[2] Univ Ottawa, Fac Med, Dept Epidemiol & Community Med, Ottawa, ON, Canada
[3] Univ Calgary, Dept Med, Libin Cardiovasc Inst, Calgary, AB, Canada
[4] Univ Calgary, Dept Community Hlth Sci, Libin Cardiovasc Inst, Calgary, AB, Canada
[5] Univ Calgary, Dept Pharmacol & Therapeut, Libin Cardiovasc Inst, Calgary, AB, Canada
关键词
antihypertensive medication; education; guidelines; hypertension; persistence; quality of care; sex-related differences; trends;
D O I
10.1016/S0828-282X(07)70801-2
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
PURPOSE: The Canadian Hypertension Education Program (CHEP) was initiated in 1999 to improve hypertension management in Canada. The objective of the present Study was to compare antihypertensive pharmacotherapy in Canada before and after the CHEP. METHODS: Data were obtained from the longitudinal National Population Health Surveys, which consisted of five cycles at two-year intervals from 1994 to 2002. Recent hypertensive respondents 20 years of age and older were identified the first time hypertension was reported or treated, and were included in a study population of 1453 newly dial-nosed hypertensive patients. Persistence with medication use was assessed in the cycle after the first report of hypertension. RESULTS: Antihypertensive medication use within two years of hypertension diagnosis increased with age, from 35% in patients 20 to 39 years of age, to 72.1% in those 80 years of age and older. Antihypertensive medication use increased after the CHEP (from 49.2% to 53.8% of the population), as did the use of multiple antihypertensive medications (from 7.5% to 10.6%). The most commonly used antihypertensive medication for men was angiotensin-converting enzyme inhibitors (beta-blockers were second), but the most common medication for women was diuretics. The overall persistence rate for antihypertensive medication use was 73.2% over two years, which had increased after the CHEP (from 70.4% to 75.4%). CONCLUSIONS: The implementation of the CHEP was followed by increased antihypertensive medication use, increased use of multiple antihypertensive medications and improved persistence with medication use. Although causality cannot be established with the design of the present study, improved hypertension management in Canada is heartening. Sex-related differences were observed in prescribed medications, even though clinical guidelines do not differentiate between sexes.
引用
收藏
页码:561 / 565
页数:5
相关论文
共 27 条
[1]  
[Anonymous], 1990, GUID ATC CLASS
[2]   Public education on hypertension: A new initiative to improve the prevention, treatment and control of hypertension in Canada [J].
Campbell, Norman R. ;
Petrella, Robert ;
Kaczorowski, Janusz .
CANADIAN JOURNAL OF CARDIOLOGY, 2006, 22 (07) :599-603
[3]   Changes in cardiovascular deaths and hospitalization in Canada [J].
Campbell, NRC ;
Onysko, J ;
Johansen, H ;
Gao, RN .
CANADIAN JOURNAL OF CARDIOLOGY, 2006, 22 (05) :425-427
[4]   The impact of the Canadian Hypertension Education Program on antihypertensive prescribing trends [J].
Campbell, NRC ;
Tu, K ;
Brant, R ;
Duong-Hua, M ;
McAlister, FA .
HYPERTENSION, 2006, 47 (01) :22-28
[5]   Temporal trends in anti hypertensive drug prescriptions in Canada before and after introduction of the Canadian Hypertension Education Program [J].
Campbell, NRC ;
McAlister, FA ;
Brant, R ;
Levine, M ;
Drouin, D ;
Feldman, R ;
Herman, R ;
Zarnke, K .
JOURNAL OF HYPERTENSION, 2003, 21 (08) :1591-1597
[6]  
CAMPBELL NRC, 2005, HYPERTENSION CANADA, V82, P1
[7]  
Caro JJ, 1999, CAN MED ASSOC J, V160, P31
[8]  
Caro JJ, 1999, CAN MED ASSOC J, V160, P41
[9]   Implementation of recommendations on hypertension: The Canadian Hypertension Education Program [J].
Drouin, D ;
Campbell, NR ;
Kaczorowski, J .
CANADIAN JOURNAL OF CARDIOLOGY, 2006, 22 (07) :595-598
[10]   ACE inhibitors and congenital anomalies [J].
Friedman, J. M. .
NEW ENGLAND JOURNAL OF MEDICINE, 2006, 354 (23) :2498-2500